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First isolated from human gastric juice in 1993 by Croatian researchers, this 15-amino acid peptide demonstrates remarkable tissue-protective properties across multiple organ systems

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IL-23 is indispensable in the survival, amplification and pathogenicity of Th17 cells in the late stage of Th17 differentiation[22].On the contrary, induced Treg (iTreg) cells is driven by high concentrations of TGF-, T-cell receptor (TCR) signaling and IL-2